PT - JOURNAL ARTICLE AU - Zoubin Ghahramani AU - Daniel M. Wolpert AU - Michael I. Jordan TI - Generalization to Local Remappings of the Visuomotor Coordinate Transformation AID - 10.1523/JNEUROSCI.16-21-07085.1996 DP - 1996 Nov 01 TA - The Journal of Neuroscience PG - 7085--7096 VI - 16 IP - 21 4099 - http://www.jneurosci.org/content/16/21/7085.short 4100 - http://www.jneurosci.org/content/16/21/7085.full SO - J. Neurosci.1996 Nov 01; 16 AB - During visually guided movement, visual representations of target location must be transformed into coordinates appropriate for movement. To investigate the representation and plasticity of the visuomotor coordinate transformation, we examined the changes in pointing behavior after local visuomotor remappings. The visual feedback of finger position was limited to one or two locations in the workspace, at which a discrepancy was introduced between the actual and visually perceived finger position. These remappings induced changes in pointing, which were largest near the locus of remapping and decreased away from it. This pattern of spatial generalization highly constrains models of the computation of the visuomotor transformation in the CNS. A simple model, in which the transformation is computed via the population activity of a set of units with large sensory receptive fields, is shown to capture the observed pattern.