PT  - JOURNAL ARTICLE
AU  - Pezawas, Lukas
AU  - Verchinski, Beth A.
AU  - Mattay, Venkata S.
AU  - Callicott, Joseph H.
AU  - Kolachana, Bhaskar S.
AU  - Straub, Richard E.
AU  - Egan, Michael F.
AU  - Meyer-Lindenberg, Andreas
AU  - Weinberger, Daniel R.
TI  - The Brain-Derived Neurotrophic Factor val66met Polymorphism and Variation in Human Cortical Morphology
AID  - 10.1523/JNEUROSCI.2680-04.2004
DP  - 2004 Nov 10
TA  - The Journal of Neuroscience
PG  - 10099--10102
VI  - 24
IP  - 45
4099  - http://www.jneurosci.org/content/24/45/10099.short
4100  - http://www.jneurosci.org/content/24/45/10099.full
SO  - J. Neurosci.2004 Nov 10; 24
AB  - A variation in the BDNF gene (val66met) affects the function of BDNF in neurons, predicts variation in human memory, and is associated with several neurological and psychiatric disorders. Here, we show that, in magnetic resonance imaging scans of a large sample of normal individuals, this polymorphism affects the anatomy of the hippocampus and prefrontal cortex, identifying a genetic mechanism of variation in brain morphology related to learning and memory.