RT Journal Article
SR Electronic
T1 Trial-by-Trial Coupling of Concurrent Electroencephalogram and Functional Magnetic Resonance Imaging Identifies the Dynamics of Performance Monitoring
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 11730
OP 11737
DO 10.1523/JNEUROSCI.3286-05.2005
VO 25
IS 50
A1 Debener, Stefan
A1 Ullsperger, Markus
A1 Siegel, Markus
A1 Fiehler, Katja
A1 von Cramon, D. Yves
A1 Engel, Andreas K.
YR 2005
UL http://www.jneurosci.org/content/25/50/11730.abstract
AB Goal-directed behavior requires the continuous monitoring and dynamic adjustment of ongoing actions. Here, we report a direct coupling between the event-related electroencephalogram (EEG), functional magnetic resonance imaging (fMRI), and behavioral measures of performance monitoring in humans. By applying independent component analysis to EEG signals recorded simultaneously with fMRI, we found the single-trial error-related negativity of the EEG to be systematically related to behavior in the subsequent trial, thereby reflecting immediate behavioral adjustments of a cognitive performance monitoring system. Moreover, this trial-by-trial EEG measure of performance monitoring predicted the fMRI activity in the rostral cingulate zone, a brain region thought to play a key role in processing of response errors. We conclude that investigations of the dynamic coupling between EEG and fMRI provide a powerful approach for the study of higher order brain functions.