RT Journal Article
SR Electronic
T1 Local Morphology Predicts Functional Organization of the Dorsal Premotor Region in the Human Brain
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 2724
OP 2731
DO 10.1523/JNEUROSCI.4739-05.2006
VO 26
IS 10
A1 Amiez, Céline
A1 Kostopoulos, Penelope
A1 Champod, Anne-Sophie
A1 Petrides, Michael
YR 2006
UL http://www.jneurosci.org/content/26/10/2724.abstract
AB A confusing picture of the functional organization of the dorsal premotor region of the human brain emerged when functional neuroimaging studies that either examined visuomotor hand conditional activity or attempted to localize the human frontal eye field reported activity increases at the same general location, namely the junction of the superior precentral sulcus with the superior frontal sulcus. The present functional magnetic resonance imaging study examined visuomotor hand conditional activity and the locus of the frontal eye field as defined by a standard task, on a subject-by-subject basis, to clarify their location and reveal relationships between the pattern of local morphology and functional activity. The results demonstrate that visuomotor hand conditional activity and the frontal eye field lie within distinct parts of the superior precentral sulcus, revealing an organization of the human premotor cortex consistent with that observed in experimental studies in the monkey.