RT Journal Article
SR Electronic
T1 Off-Line Processing: Reciprocal Interactions between Declarative and Procedural Memories
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 10468
OP 10475
DO 10.1523/JNEUROSCI.2799-07.2007
VO 27
IS 39
A1 Brown, Rachel M.
A1 Robertson, Edwin M.
YR 2007
UL http://www.jneurosci.org/content/27/39/10468.abstract
AB The acquisition of declarative (i.e., facts) and procedural (i.e., skills) memories may be supported by independent systems. This same organization may exist, after memory acquisition, when memories are processed off-line during consolidation. Alternatively, memory consolidation may be supported by interactive systems. This latter interactive organization predicts interference between declarative and procedural memories. Here, we show that procedural consolidation, expressed as an off-line motor skill improvement, can be blocked by declarative learning over wake, but not over a night of sleep. The extent of the blockade on procedural consolidation was correlated to participants' declarative word recall. Similarly, in another experiment, the reciprocal relationship was found: declarative consolidation was blocked by procedural learning over wake, but not over a night of sleep. The decrease in declarative recall was correlated to participants' procedural learning. These results challenge the concept of fixed independent memory systems; instead, they suggest a dynamic relationship, modulated by when consolidation takes place, allowing at times for a reciprocal interaction between memory systems.