PT  - JOURNAL ARTICLE
AU  - Robert A. Cornell
AU  - Michelle Aarts
AU  - Diana Bautista
AU  - Jaime García-Añoveros
AU  - Kirill Kiselyov
AU  - Emily R. Liman
TI  - A Double TRPtych: Six Views of Transient Receptor Potential Channels in Disease and Health
AID  - 10.1523/JNEUROSCI.3929-08.2008
DP  - 2008 Nov 12
TA  - The Journal of Neuroscience
PG  - 11778--11784
VI  - 28
IP  - 46
4099  - http://www.jneurosci.org/content/28/46/11778.short
4100  - http://www.jneurosci.org/content/28/46/11778.full
SO  - J. Neurosci.2008 Nov 12; 28
AB  - At the 2008 Annual Meeting of the Society for Neuroscience, a Mini-Symposium entitled “Contributions of TRP Channels to Neurological Disease” included talks from six heads of newly established laboratories, each with a unique research focus, model system, and set of experimental tools. Some of the questions addressed in these talks include the following. What is the role of transient receptor potential (TRP) channels in pain perception? How do normally functioning TRP channels contribute to cell death pathways? What are the characteristics of TRPpathies, disease states that result from overactive or underactive TRP channels? How are TRP channels regulated by signal transduction cascades? This review summarizes recent results from those laboratories and provides six perspectives on the subject of TRP channels and disease.