PT  - JOURNAL ARTICLE
AU  - Rohrer, H
AU  - Acheson, AL
AU  - Thibault, J
AU  - Thoenen, H
TI  - Developmental potential of quail dorsal root ganglion cells analyzed in vitro and in vivo
AID  - 10.1523/JNEUROSCI.06-09-02616.1986
DP  - 1986 Sep 01
TA  - The Journal of Neuroscience
PG  - 2616--2624
VI  - 6
IP  - 9
4099  - http://www.jneurosci.org/content/6/9/2616.short
4100  - http://www.jneurosci.org/content/6/9/2616.full
SO  - J. Neurosci.1986 Sep 01; 6
AB  - The cell types present in quail dorsal root ganglia during early development were identified using markers for neurons, glial cells, and fibroblasts (Rohrer et al., 1985). Using the quail-chick transplantation technique, the potential of quail dorsal root ganglion cells to differentiate to adrenergic chromaffin cells, as identified by tyrosine hydroxylase immunostaining, was analyzed. A population of undifferentiated cells, which is present in quail dorsal root ganglia at embryonic day 5, was separated from neurons and glial cells. We show that this population contains cells that differentiate to adrenergic chromaffin cells after back-transplantation into 2-d-old chick embryos. A large proportion of these undifferentiated cells also differentiates to neurons in vitro. Precursors for adrenal chromaffin cells and for neurons are present in dorsal root ganglia in significant numbers only during early development.