RT Journal Article
SR Electronic
T1 Long-Distance Amplitude Correlations in the High Gamma Band Reveal Segregation and Integration within the Reading Network
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 6421
OP 6434
DO 10.1523/JNEUROSCI.4363-11.2012
VO 32
IS 19
A1 Juan R. Vidal
A1 Samson Freyermuth
A1 Karim Jerbi
A1 Carlos M. Hamamé
A1 Tomas Ossandon
A1 Olivier Bertrand
A1 Lorella Minotti
A1 Philippe Kahane
A1 Alain Berthoz
A1 Jean-Philippe Lachaux
YR 2012
UL http://www.jneurosci.org/content/32/19/6421.abstract
AB Reading sentences involves a distributed network of brain regions acting in concert surrounding the left sylvian fissure. The mechanisms of neural communication underlying the extraction and integration of verbal information across subcomponents of this reading network are still largely unknown. We recorded intracranial EEG activity in 12 epileptic human patients performing natural sentence reading and analyzed long-range corticocortical interactions between local neural activations. During a simple task contrasting semantic, phonological, and purely visual processes, we found process-specific neural activity elicited at the single-trial level, characterized by energy increases in a broad gamma band (40–150 Hz). Correlation analysis between task-induced gamma-band activations revealed a selective fragmentation of the network into specialized subnetworks supporting sentence-level semantic analysis and phonological processing. We extend the implications of our results beyond reading, to propose that gamma-band amplitude correlations might constitute a fundamental mechanism for large-scale neural integration during high-level cognition.