RT Journal Article
SR Electronic
T1 Emergence of Sensory Patterns during Sleep Highlights Differential Dynamics of REM and Non-REM Sleep Stages
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 14715
OP 14728
DO 10.1523/JNEUROSCI.0232-13.2013
VO 33
IS 37
A1 Ramot, Michal
A1 Fisch, Lior
A1 Davidesco, Ido
A1 Harel, Michal
A1 Kipervasser, Svetlana
A1 Andelman, Fani
A1 Neufeld, Miri Y.
A1 Kramer, Uri
A1 Fried, Itzhak
A1 Malach, Rafael
YR 2013
UL http://www.jneurosci.org/content/33/37/14715.abstract
AB Despite the profound reduction in conscious awareness associated with sleep, sensory cortex remains highly active during the different sleep stages, exhibiting complex interactions between different cortical sites. The potential functional significance of such spatial patterns and how they change between different sleep stages is presently unknown. In this electrocorticography study of human patients, we examined this question by studying spatial patterns of activity (broadband gamma power) that emerge during sleep (sleep patterns) and comparing them to the functional organization of sensory cortex that is activated by naturalistic stimuli during the awake state. Our results show a high correlation (p < 10−4, permutation test) between the sleep spatial patterns and the functional organization found during wakefulness. Examining how the sleep patterns changed through the night highlighted a stage-specific difference, whereby the repertoire of such patterns was significantly larger during rapid eye movement (REM) sleep compared with non-REM stages. These results reveal that intricate spatial patterns of sensory functional organization emerge in a stage-specific manner during sleep.