RT Journal Article
SR Electronic
T1 Interhemispheric Interactions of the Human Thalamic Reticular Nucleus
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 2026
OP 2032
DO 10.1523/JNEUROSCI.2623-14.2015
VO 35
IS 5
A1 Joseph D. Viviano
A1 Keith A. Schneider
YR 2015
UL http://www.jneurosci.org/content/35/5/2026.abstract
AB The thalamic reticular nucleus is an important structure governing the recurrent interactions between the thalamus and cortex that may provide a substrate for unified perception. Despite the importance of the TRN, its activity has been scarcely investigated in vivo in animal models, and never in humans. Here we anatomically identify the human TRN using multiple registered and averaged proton density-weighted structural MRI scans and drive its functional activity with a dual phase-encoded stimulus. We characterize the retinotopic and temporal response properties in the visual sector of the TRN and measured an inhibitory relationship with the contralateral LGN. These observations provide a basis for further gross characterizations of the role of the TRN in human behavior.