RT Journal Article
SR Electronic
T1 The State of the NIH BRAIN Initiative
JF The Journal of Neuroscience
JO J. Neurosci.
FD Society for Neuroscience
SP 6427
OP 6438
DO 10.1523/JNEUROSCI.3174-17.2018
VO 38
IS 29
A1 Koroshetz, Walter
A1 Gordon, Joshua
A1 Adams, Amy
A1 Beckel-Mitchener, Andrea
A1 Churchill, James
A1 Farber, Gregory
A1 Freund, Michelle
A1 Gnadt, Jim
A1 Hsu, Nina S.
A1 Langhals, Nicholas
A1 Lisanby, Sarah
A1 Liu, Guoying
A1 Peng, Grace C.Y.
A1 Ramos, Khara
A1 Steinmetz, Michael
A1 Talley, Edmund
A1 White, Samantha
YR 2018
UL http://www.jneurosci.org/content/38/29/6427.abstract
AB The BRAIN Initiative arose from a grand challenge to “accelerate the development and application of new technologies that will enable researchers to produce dynamic pictures of the brain that show how individual brain cells and complex neural circuits interact at the speed of thought.” The BRAIN Initiative is a public-private effort focused on the development and use of powerful tools for acquiring fundamental insights about how information processing occurs in the central nervous system (CNS). As the Initiative enters its fifth year, NIH has supported >500 principal investigators, who have answered the Initiative's challenge via hundreds of publications describing novel tools, methods, and discoveries that address the Initiative's seven scientific priorities. We describe scientific advances produced by individual laboratories, multi-investigator teams, and entire consortia that, over the coming decades, will produce more comprehensive and dynamic maps of the brain, deepen our understanding of how circuit activity can produce a rich tapestry of behaviors, and lay the foundation for understanding how its circuitry is disrupted in brain disorders. Much more work remains to bring this vision to fruition, and the National Institutes of Health continues to look to the diverse scientific community, from mathematics, to physics, chemistry, engineering, neuroethics, and neuroscience, to ensure that the greatest scientific benefit arises from this unique research Initiative.