PT - JOURNAL ARTICLE AU - Özdemir, Şahcan AU - Şentürk, Yağmur Damla AU - Ünver, Nursima AU - Demircan, Can AU - Olivers, Christian N. L. AU - Egner, Tobias AU - Günseli, Eren TI - Effects of Context Changes on Memory Reactivation AID - 10.1523/JNEUROSCI.2096-23.2024 DP - 2024 Sep 04 TA - The Journal of Neuroscience PG - e2096232024 VI - 44 IP - 36 4099 - http://www.jneurosci.org/content/44/36/e2096232024.short 4100 - http://www.jneurosci.org/content/44/36/e2096232024.full SO - J. Neurosci.2024 Sep 04; 44 AB - While the influence of context on long-term memory (LTM) is well documented, its effects on the interaction between working memory (WM) and LTM remain less understood. In this study, we explored these interactions using a delayed match-to-sample task, where participants (6 males, 16 females) encountered the same target object across six consecutive trials, facilitating the transition from WM to LTM. During half of these target repetitions, the background color changed. We measured the WM storage of the target using the contralateral delay activity in electroencephalography. Our results reveal that task-irrelevant context changes trigger the reactivation of long-term memories in WM. This reactivation may be attributed to content–context binding in WM and hippocampal pattern separation.