Table 2.

Motor nerve conduction velocities (MNCVs) and compound muscle action potentials (CMAPs), measured in the hind legs of transgenic (V01 and V05) and wild-type mouse strains

Mouse strainParesisMNCV (m/sec) mean (range)Distal latency (msec) mean (range)CMAP amplitude (mV) mean (range)
Wild typeImmature2_a n = 5No27.7 (15.2–36.6)1.2 (1.0–1.4)3.8 (2.0–6.1)
Wild typeAdult2_b n = 3No37.5 (31.9–40.6)1.2 (1.1–1.4)6.2 (1.6–10.3)
V01Immature n = 5No16.6 (11.5–22.0)1.6 (1.2 –1.9)3.3 (1.3–5.4)
V01Adult n = 2No12.6 (12.0–13.1)1.7 (1.1–2.2)1.6 (1.4–1.8)
V01V01Immature n = 2Yes3.9 (3.5–4.2)2.5 (2.5)0.3 (0.2–0.4)
V05Adult n = 2Yes4.4 (3.6–5.2)4.4 (3.8–4.9)0.9 (0.1–1.7)
  • F2_a 1–2 months of age.

  • F2_b Above 2 months of age.