Table 2.

MK801 pretreatment versus controls

Experimental groupAD2_150Cumulative AD duration (sec)2_150Timm score2_150
Normal control (n = 7)−−0.8  ± 0.13
Kindling17.2  ± 1.8624  ± 543.44  ± 0.29
1 Cl V
(n = 9)
MK80117840  ± 582_a2.43  ± 0.322_b
0–17 ADs
(n = 7)
MK80124.2  ± 1.71166  ± 1102_c3.39  ± 0.22
10 AD–1 Cl V
(n = 9)
Kindling29.3  ± 1.61451  ± 833.54  ± 0.3
10 Cl V
(n = 8)
MK80135.7  ± 1.92066  ± 482_d3.29  ± 0.27
1–10 Cl V
(n = 9)

  • ↵F2_150 p < 0.0001, ANOVA.

  • ↵F2_a  versus kindling 1 Cl V, p < 0.017.

  • ↵F2_b  versus kindling 1 Cl V, p < 0.032.

  • ↵F2_c  versus kindling 1 Cl V, p < 0.001.

  • ↵F2_d  versus kindling 10 Cl V, p < 0.00001.