Table 3.

Effect of chronic carbamazepine (50 μm) treatment on the potentiating effect in cultures from cerebellum

Cerebellar culturesCerebellar cultures + carbamazepine (50 μm)
PE + CPA (1 μm)120  ± 15158  ± 22
PE + CPA (10 μm)117  ± 18210  ± 28
  • Data are given as percentage (mean ± SD) of the effect of PE (100 μm) (4590 ± 367 cpm for untreated cultures and 4476 ± 218 cpm for carbamazepine-treated cultures = 100%). Similar results were obtained in three independent experiments.