Drug effects on population spikes in the dentate gyrus
| Function | Drug | Dosage | Change (%) | Rats (n) |
|---|---|---|---|---|
| Agonist 1a | 8-OH-DPAT | 0.2 mg/kg | −47 ± 3.6 | 9 |
| PCPA/DPAT | 0.2 mg/kg | 59 ± 1.5 | 6 | |
| Antagonist 1a | NAN-190 | 3 mg/kg | 5 ± 2.0 | 6 |
| Agonist 1b | CGS-12066-B | 0.75 mg/kg | −1 ± 1.4 | 5 |
| Antagonist 2 | Mianserin | 5 mg/kg | 3 ± 1.6 | 5 |
| Antagonist 3 | Ondansetron | 50 μg/kg | 0 ± 1.6 | 5 |
| Ondansetron | 0.2 mg/kg | 2.3 ± 1.2 | 8 | |
| Ondansetron | 0.6 mg/kg | 2 ± 1.8 | 7 | |
| DAU 6215 | 0.2 mg/kg | 2.4 ± 2.0 | 6 | |
| DAU 6215 | 0.6 mg/kg | −7 ± 2.7 | 6 | |
| DAU 6285 | 0.2 mg/kg | 3.3 ± 1.7 | 5 | |
| DAU 6285 | 0.6 mg/kg | 3 ± 1.7 | 6 | |
| Agonist 4 | BIMU 1 | 0.6 mg/kg | −1 ± 1.6 | 4 |