Table 1.

Conductance properties of recombinant AMPA receptors formed from GluR2 and GluR4

UneditedEdited
ReceptorConductance (pS)AgonistReceptorConductance (pS)Agonist
GluR4Q(i)7/16/27AMPAGluR2R(i)0.21*AMPA
8/15/24Glutamate0.36*Glutamate
2.5*Kainate0.45*Kainate
GluR4Q(o)4.0*KainateGluR2R(o)<0.3*Kainate
GluR2Q(o)/4Q(i)7/15/24AMPAGluR2R(o)/4Q(i)4/9AMPA
8/17/26Glutamate4/10Glutamate
GluR2R(i)/4Q(i)4/8AMPA
∼4/10Glutamate
0.50*Kainate
GluR2R(i)/4Q(o)1.0*Glutamate
  • Single-channel conductance values were obtained either from time-course fitting or noise analysis (indicated by asterisk) when channel events were too small to be resolved directly.