Table 1.

Frequency of [Ca2+] oscillations and its relative change in astrocytes after three consecutivet-ACPD applications

Number of astrocytesOscillation frequency mean ± SE I pulseChange in frequency (%) mean ± SE II pulseChange in frequency (%) mean ± SE III pulse
CA1132 (20)1.55  ± 0.11+28.4  ± 5.6+44.7  ± 8.7
CA1 subpopulation57 (20)0.66  ± 0.02+46.2  ± 7.9+98.8  ± 13.7
Visual cortex15 (4)1.05  ± 0.13+47.4  ± 13.1+53  ± 7.41
CA1 (3 hr interval)19 (2)0.80  ± 0.11+62.7  ± 13.4   ND
  • The time interval between stimuli, unless specified, was 10 min. Values in the second and third pulse column indicate the average increase in oscillation frequency in the second and third pulse, respectively, as compared with the oscillation frequency in the first pulse. Numbers in parentheses indicate the number of experiments. ND, Not determined.