Table 1.

The effect of intraperitoneal NGF (IP NGF) or intrathecal NGF on the percentage of DRG cells expressing BDNF mRNA, BDNF immunoreactivity, or trkA immunoreactivity

ControlIP NGFIntrathecal NGF
BDNF immunoreactivity22.3  ± 1.2% (3)22.3  ± 3.3% (3)40  ± 1.5% (4)1-160
BDNF mRNA28.5  ± 3.3% (4)43.7  ± 4.4% (3)*37.8  ± 1.4% (4)*
TrkA immunoreactivity37.8  ± 2.2% (4)37.5  ± 2.0% (4)42.3  ± 3.1% (3)
  • The figures in brackets indicate the number of animals analyzed.

  • *  indicates significantly different from controls at p< 0.05;

  • F1-160  indicates p < 0.001.