Table 1.

Eye abnormalities and deaths in dominant negative trkB receptor mutants: rescue by wild-type receptors

cRNA injectedEye abnormalities [% (n)]Deaths (%)
Uninjected controls (11/243)3 (3/99)5
H2O-injected controls (11/216)8 (8/100)5
TrkBMut (2 ng/embryo) (108/378)40 (27/67)29
TrkBMut:WT (2:2 ng/embryo) (51/396)14 (21/154)13