DRG counts | Peripherin (+) | Total cells |
---|---|---|
Wild-type | 2729 ± 292 | 13,455 ± 296 |
NT-3 mutant | 1806 ± 108 | 9505 ± 779 |
Reduction (%) | 34% | 29% |
Embryonic dorsal root ganglia (L4) cells were counted in E13–E13.25 wild-type and mutant embryos. Peripherin-positive neurons represents 20 and 19% of wild-type and NT-3−/− DRG cells, respectively. Student’s t test determined a significance ofp < 0.005; n = 3.