Stereotaxic coordinates used to lesion the orbital and lateral prefrontal cortex
| AP (mm) | LM (mm) | Angle | Position of cannula from base of skull (mm) | Volume of quinolinic acid injected (μl) |
|---|---|---|---|---|
| Orbital prefrontal lesion | ||||
| +16.00 | ±4.0 | 0.8 | 0.4 | |
| +16.00 | ±2.0 | 0.7 | 0.5 | |
| +16.75 | ±3.0 | 0.7 | 0.6 | |
| +17.75 | ±2.0 | 0.7 | 0.6 | |
| +18.50 | ±2.0 | 0.7 | 0.5 | |
| Lateral prefrontal lesion | ||||
| +16.00 | ±6.2 | 10° | 0.9 | 1.0 |
| +16.75 | ±5.9 | 8° | 1.0 | 0.6 |
| +16.75 | ±5.9 | 8° | 1.5 | 0.6 |
| +17.50 | ±5.6 | 8° | 1.0 | 1.0 |
| +18.25 | ±5.3 | 8° | 1.0 | 1.5 |
| +19.00 | ±4.6 | 8° | 0.7 | 0.8 |
| +20.00 | ±3.0 | Upright | 1.7 | 0.5 |
All coordinates were adjusted accordingly, in line with the “depth check” coordinate, as discussed in Materials and Methods.