Table 1.

Abbreviations of agents used

Abbreviation(s)AgentAction
PGE2or E2Prostaglandin E2Hyperalgesic inflammatory mediator
DAMGO or D[d-Ala2,N-Me-Phe4,gly5-ol] enkephalinμ-opioid receptor agonist
NNaloxoneOpioid receptor antagonist
ClClonidineα2-adrenergic agonist
YoYohimbineα2-adrenergic antagonist
CPAN6-cyclopentyl-adenosineA1-adenosine receptor agonist
PACPX1,3-dipropyl-8-(2-amino-4-chlorophenyl)-xanthineA1-adenosine receptor antagonist
μ-antisenseμ-opioid receptor oligodeoxynucleotide (ODN)Downregulation of μ-opioid receptors
μ-senseNo effect
α2-antisenseα2C-adrenergic receptor oligodeoxynucleotide (ODN)Downregulation of α2C-adrenergic receptors
α2-senseNo effect