Abbreviations of agents used
| Abbreviation(s) | Agent | Action |
|---|---|---|
| PGE2or E2 | Prostaglandin E2 | Hyperalgesic inflammatory mediator |
| DAMGO or D | [d-Ala2,N-Me-Phe4,gly5-ol] enkephalin | μ-opioid receptor agonist |
| N | Naloxone | Opioid receptor antagonist |
| Cl | Clonidine | α2-adrenergic agonist |
| Yo | Yohimbine | α2-adrenergic antagonist |
| CPA | N6-cyclopentyl-adenosine | A1-adenosine receptor agonist |
| PACPX | 1,3-dipropyl-8-(2-amino-4-chlorophenyl)-xanthine | A1-adenosine receptor antagonist |
| μ-antisense | μ-opioid receptor oligodeoxynucleotide (ODN) | Downregulation of μ-opioid receptors |
| μ-sense | No effect | |
| α2-antisense | α2C-adrenergic receptor oligodeoxynucleotide (ODN) | Downregulation of α2C-adrenergic receptors |
| α2-sense | No effect |