PPE and PPD mRNA levels in day 60 fetal rhesus macaques
| Brain area | PPE (fg/μg) | PPD (fg/μg) | ||
|---|---|---|---|---|
| Saline | Cocaine | Saline | Cocaine | |
| A1 | 97.17 ± 9.51 | 225.23 ± 26.49* | 73.7 ± 9.9 | 114.13 ± 8.47* |
| A2 | 337.63 ± 21.72 | 395.9 ± 21.53 | 65.86 ± 7.6 | 82.1 ± 9.23 |
| A3 | 144.02 ± 22.95 | 198.9 ± 20.69 | 0.0 ± 0.0 | 0.0 ± 0.0 |
| A4 | 252.8 ± 24.51 | 315.0 ± 13.65 | 43.16 ± 6.03 | 52.86 ± 12.26 |
| A5 | 353.9 ± 24.48 | 430.77 ± 27.63 | 54.26 ± 6.98 | 68.43 ± 6.63 |
| A6 | 400.1 ± 28.12 | 334.2 ± 28.67 | 59.3 ± 4.58 | 44.03 ± 4.81 |
The quantities of PPE and PPD mRNA were determined in total RNA extracts from dissected brain areas A1–A6 in saline- and cocaine-treated day 60 fetal monkeys. A1–A6, Areas through the brain from rostral A1 to caudal A6. The numbers are expressed as mean ± SEM.
↵* p < 0.05 versus saline controls.