dlPFC | mPFC | lOrb | pLimb | |
---|---|---|---|---|
Saline | 0.26 ± 0.07 | 0.65 ± 0.22 | 1.75 ± 0.13 | 0.71 ± 0.15 |
PCP | 0.25 ± 0.02 | 0.65 ± 0.09 | 1.66 ± 0.58 | 0.71 ± 0.13 |
S-(−)HA/PCP | 0.43 ± 0.02 | 0.92 ± 0.11 | 1.34 ± 0.37 | 0.88 ± 0.05 |
Whereas PCP increased DA turnover in the dlPFC, mPFC, lOrb, and pLimb of the monkey brain, it had no significant effect either alone, or in combination with S-(−)HA966, on DA concentrations, indicating that the effects are driven by changes in HVA levels. Results are expressed as mean DA concentrations in ng/mg protein ± SEM.