Table 1.

BDNF in the olfactory bulb, cortex, and hippocampal formation

BDNF-ir fibersBDNF-ir cellsBDNF mRNA
Mitral cell layer2/l0
Internal granule layer04/l
Glomerular layer (periglomerular)1/l2/l
External plexiform/tufted cells00
Granule cell layer of AOB±2/l–m0
Anterior olfactory nucleus+3/m3–4/h
Orbital cortex3/l2–3/m
Insular cortex (granular + agranular)3/l–m3/m–h
Frontal cortex3/m3/m
Cingulate cortex3/l–m3–4/h
Piriform cortex3/m3–4/h
Parietal cortex3/l2–3/m
Perirhinal cortex3/l–m3/m–h
Retrosplenial cortex3/l3/m
Occipital cortex2–3/l2–3/m
Temporal cortex3/l2–3/m
Entorhinal cortex3/m–h3/m–h
Endopiriform nucleus (dorsal/ventral)2–3/m3/h
Tenia tecta (rostral part)3/m4/h
Tenia tecta (caudal part)04/l
Indusium griseum2/l–m1/m
CA1-stratum oriens++1/l0
CA1-stratum pyramidale2/l–m3–4/m
CA1-stratum radiatum++00
CA1-stratum lacunosum moleculare++00
CA2-stratum oriens++1/m0
CA2-stratum pyramidale3/l–m4/h
CA2-stratum lucidum+++++00
CA3-stratum oriens++1/m0
CA3-stratum pyramidale4/m–h4/h
CA3-stratum lucidum+++++00
Dentate gyrus-polymorph layer/hilus+++++1-1601–2/h
Dentate gyrus-granule cell layer4/l–m4/m
Dentate gyrus-inner molecular layer++++0–1/m0
Dentate gyrus-middle molecular layer+00
Dentate gyrus-outer molecular layer00
  • Fibers: −, none; +, very light staining; ++, light staining; +++, moderate staining; ++++, heavy staining; +++++, extremely heavy staining. Cells: 0, no cells observed; 1, occasional cells; 2, few scattered cells; 3, moderate number of cells; 4, densely packed cells;

  • F1-160 , could not be determined. l, Lightly stained; m, moderately stained; h, heavily stained.