Table 4.

BDNF in the hypothalamus and epithalamus

BDNF-ir fibersBDNF-ir cellsBDNF mRNA
Medial habenular neucleus+++++00
Lateral habenular nucleus+1–2/lLight haze
Anterior hypothalamic area, anterior++1/l0
Lateroanterior hypothalamic nucleus++1/l2–3/l
Lateral hypothalamic area++1/m2/l
Anterior hypothalamic area, central++00
Paraventricular hypothalamic nucleus (parvocellular)++/+++1/m3/m
Paraventricular hypothalamic nucleus, lateral (magnocellular)+00
Medial tuberal nucleus++1/l–m2–3/m
Tuber cinereum area++1/l–m2–3/l–m
Ventromedial hypothalamic nucleus++2/m–h3/h
Arcuate hypothalamic nucleus+++00
Median eminance+/++00
Dorsomedial hypothalamic nucleus, diffuse++1/m3/l–m
Dorsal hypothalamic area++1/m1/l
Perifornical nucleus++01/m
Premammillary nucleus++02–3/m–h
Supramammillary nucleus++2/m3/h
Medial mammillary nucleus4/l–m3–4/m–h
Lateral mammillary nucleus4/l3–4/m
Interpeduncular nucleus+00
Posterior hypothalamic area++2/l–m3/m
Infundibular stem+/++00
  • Fibers: −, none; +, very light staining; ++, light staining; +++, moderate staining; ++++, heavy staining; +++++, extremely heavy staining. Cells: 0, no cells observed; 1, occasional cells; 2, few scattered cells; 3, moderate number of cells; 4, densely packed cells;

  • F4-160 , could not be determined. l, Lightly stained; m, moderately stained; h, heavily stained.