Modulation of neuronal activity
Neuronal type | ON | ON–OFF | OFF | |
Number of cells with significant modulation | ||||
Inhibition | 7 of 24 | 9 of 15 | 9 of 14 | |
Excitation | 5 of 24 | 0 of 15 | 0 of 14 |
Inhibition | Excitation | Inhibition | Inhibition | |
Magnitude of cell modulation | ||||
No Ca2+wavea | +3 ± 5% (30) | −1 ± 3% (20) | +1 ± 2% (39) | −1 ± 1% (36) |
Large Ca2+ waveb | −35 ± 3% (35) | +27 ± 5% (27) | −25 ± 3% (35) | −25 ± 2% (44) |
Number of cells. For each cell tested, modulation was judged significant if the modulation in those trials when a Ca2+wave reached the cell (ΔF/F Ca2+signal > 22%) was significantly different than when a Ca2+ wave failed to reach the cell (ΔF/F < 1%) (p < 0.05).
Magnitude of cell modulation. Shown are the average modulation values for trials in cells with statistically significant modulation. Separate means are given for trials when a Ca2+ wave reached the cell and did not reach the cell. For ON neurons, separate means are given for cells with excitatory and inhibitory modulation.
F1-a Trials when the ΔF/FCa2+ signal was <1%.
F1-1002 Trials when ΔF/F was >22%.