Table 1.

Dose-dependent effects of inhibitors on growth cone migration on fibronectin

ConditionsGrowth cone velocity (μm/hr)
Control32  ± 41-b
2 mm EGTA33  ± 3
5 mm EGTA22  ± 31-a
2 mmNi2+29  ± 7
4 mmNi2+23  ± 61-a
2 mm Co2+33  ± 9
4 mmCo2+15  ± 41-a
2 μm BAPTA33  ± 3
4 μmBAPTAnd
10 μm FPC29  ± 4
20 μm FPC7  ± 31-a
2 μm KN-6231  ± 3
4 μmKN-6213  ± 21-a
  • F1-a  Parallel control experiments were performed for each inhibitor (t test).

  • F1-b  Average growth cone velocity of all control experiments. nd, Not determined. 4 μm BAPTA significantly changed growth cone morphology.