Table 2.

Effects of drugs on interspike intervals

Control (msec)Drug (msec)
CsCl (1 mm)162  ± 5  (5)151  ± 2  (5)
CoCl2 (0.5 mm)113  ± 1  (4)102  ± 1  (4)
Charybdotoxin (10 nm)174  ± 6  (5)159  ± 4  (5)*
Apamin (1 μm)169  ± 3  (5)168  ± 3  (5)
TEA (0.5 mm)162  ± 5  (5)148  ± 3  (5)*
TEA (40 mm)139  ± 3  (6)147  ± 2  (6)
4-Aminopyridine (100 μm)144  ± 4  (5)85  ± 1  (5)*
  • One hundred successive interspike intervals were measured per cell, and the number of cells is given in parentheses. Data represent mean ± SEM of pooled measurements.

  • *Significant differences (p < 0.01,t test).