Table 2.

Two-way ANOVA of analgesic responses

GenotypeTreatmentInteraction
FPFPFP
δ-Agonists
 Analgesic response
  Tail immersion(1,2)  = 3.00N.S.(2,44) = 8.46<0.001(2,44)  = 0.38N.S.
  Hot plate
   Licking(1,2)  = 0.86N.S.(2,44) = 21.50<0.0001(2,44)  = 0.12N.S.
   Jumping(1,2)  = 4.85<0.05(2,44) = 24.58<0.0001(2,44)  = 1.33N.S.
 Naltrindole antagonism
  Tail immersion(1,3)  = 1.34N.S.(3,49) = 15.15<0.0001(3,49)  = 3.03<0.05
  Hot plate
   Licking(1,3)  = 0.93N.S.(3,49) = 16.32<0.0001(3,49)  = 0.93N.S.
   Jumping(1,3)  = 2.36N.S.(3,49) = 22.85<0.0001(3,49)  = 2.49N.S.
κ-Agonist
 Analgesic response
  Tail immersion(1,1)  = 3.74N.S.(1,28) = 37.53<0.0001(1,28)  = 0.15N.S.
  Hot plate
   Licking(1,1)  = 0.35N.S.(1,28) = 111.02<0.0001(1,28)  = 0.24N.S.
   Jumping(1,1)  = 0.13N.S.(1,28) = 42.65<0.0001(1,28)  = 1.02N.S.
 Norbinaltorphimine antagonism
  Tail immersion(1,3)  = 0.48N.S.(3,63) = 27.65<0.0001(3,63)  = 2.75<0.05
  Hot plate
   Licking(1,3)  = 0.81N.S.(3,63) = 84.21<0.0001(3,63)  = 0.44N.S.
   Jumping(1,3)  = 1.87N.S.(3,63) = 29.38<0.0001(3,63)  = 0.85N.S.
  • The factors of variation (between subjects) were genotype and treatment. N.S., Not significant.