Table 1.

Comparison of functional properties of K+current components in BC and PC patches

BCsPCsp
Total peak conductance density175  ± 11 pS μm−295  ± 6 pS μm−2<0.001*
Fast delayed rectifier58  ± 6%12  ± 4%<0.001*
  (33–72%)  (1–22%)
 Activation curve
  midpoint V−7.1  ± 0.9 mV−12.1  ± 1.2 mV<0.005
  k11.5  ± 0.8 mV10.0  ± 1.0 mV>0.1
(14)(9)
Slow delayed rectifier26  ± 5%27  ± 4%>0.5
  (14–40%)  (16–42%)
 Activation curve
  midpoint V3.3  ± 4.9 mV−7.5  ± 5.8 mV>0.05
  k17.3  ± 1.5 mV26.3  ± 1.8 mV<0.005
(9)(9)
 Inactivation curve
  midpoint V−63.8  ± 6.2 mV−70.0  ± 3.4 mV>0.1
  k11.1  ± 2.0 mV7.8  ± 1.7 mV>0.5
  noninact. comp.  (37 ± 5%)  (16 ± 2%)>0.05
(9)(10)
A-type17  ± 4%61  ± 4%<0.001*
  (6–24%)  (52–84%)
 Activation curve
  midpoint V−6.2  ± 3.3 mV−3.0  ± 3.6 mV>0.5
  k23.0  ± 0.7 mV27.0  ± 0.5 mV<0.05
(9)(11)
 Inactivation curve
  midpoint V−75.5  ± 2.5 mV−77.3  ± 3.2 mV>0.5
  k8.5  ± 0.8 mV7.4  ± 0.4 mV>0.5
(9)(17)
 τ recovery from inactivation30.1  ± 6.4 msec22.8  ± 2.7 msec>0.1
  (22 ± 4%)  (64 ± 3%)<0.001*
165  ± 49 msec314  ± 80 msec>0.1
  (55 ± 5%)  (16 ± 3%)<0.001*
(5)(6)
  • Values indicate mean, SEM, and total number of nucleated patches (in parentheses). Highly significant differences between BCs and PCs are indicated by asterisks. Activation curves were fitted with Boltzmann equations raised to fourth power, and inactivation curves were fitted with simple Boltzmann functions.