Table 2.

Effects of depolarization on electrophysiological properties of inferior colliculus neurons

AP amplitude (mV)AHP–RMP (mV)AP decay duration (msec)Number of APNumber of cells firing
Multiple APsSingle AP
Control104  ± 916  ± 22-a4.4  ± 0.32-a2.4  ± 0.6610
High-K treated111  ± 68  ± 32-a3.3  ± 0.32-a3.9  ± 1.454
  • The action potential amplitude, difference between the afterhyperpolarization potential and resting membrane potential, action potential decay duration, and number of action potentials were determined from the action potentials evoked by a 10 pA (or 20 pA in two control cells) depolarizing current step for 160 msec. The action potential decay duration is defined as the time from the peak of the action potential to the maximal hyperpolarization. In total, 16 control cells and 9 high-K-treated cells were examined.

  • F2-a  The control values are different from that determined in high-K-treated cells; p < 0.05 (two-tailed Student’s t test).