Table 2.

Effects of nNOS knock-out and MK-801 administration on parameters of dendritic growth

+/+ saline (n = 48)−/− saline (n = 33)+/+ MK-801 (n = 43)−/− MK-801 (n = 45)
Number of primary dendrites (ns)3.7  ± 0.23.8  ± 0.23.6  ± 0.13.8  ± 0.2
Number of bifurcations (p < 0.001)10.3  ± 0.58.6  ± 0.6*7.4  ± 0.5*7.1  ± 0.4*
Total arborization (μm) (p < 0.001)2668  ± 1082372  ± 1112186  ± 111*2080  ± 119*
Longest dendrite (μm) (ns)446  ± 12401  ± 12424  ± 11425  ± 18
Cell body area (μm2) (p < 0.001)617  ± 47719  ± 54464  ± 35*546  ± 41**
  • Results are mean ± SEM. Results of group comparisons made using ANOVA are indicated in parentheses after parameter. ns indicates no significant difference between groups. *indicates significant difference from +/+ saline, ** indicates significant difference from −/− saline (p < 0.05; Student-Newman–Keuls).