Table 1.

EC50 and Hill values for glutamate and glycine

GlutamateGlycine
EC50m)nHnEC50m)nHn
NR1/NR2A2.89  ±  0.121.49  ± 0.0982.62  ± 0.191.54  ± 0.156
NR1/NR2A(N463A)17.9  ±  1.41.70  ± 0.1832.50  ± 0.161.78  ± 0.184
NR1/NR2A(K465E)29.3  ±  1.41.91  ± 0.1843.11  ± 0.271.64  ± 0.203
NR1/NR2A(H466A)624  ±  321.55  ± 0.0963.67  ± 0.221.54  ± 0.124
NR1/NR2A(H466F)38.4  ±  4.61.09  ± 0.1042.10  ± 0.221.69  ± 0.243
NR1/NR2A(G664A)2.08  ±  0.251.46  ± 0.2131.69  ± 0.211.44  ± 0.213
NR1/NR2A(T665A)19.0  ±  2.01.18  ± 0.1133.86  ± 0.391.39  ± 0.155
NR1/NR2A(V666A)33.4  ±  1.61.12  ± 0.0554.53  ± 0.311.35  ± 0.104
NR1/NR2A(G669A)927  ±  461.38  ± 0.0743.58  ± 0.231.39  ± 0.104
NR1/NR2A(S670A)4.97  ±  0.301.35  ± 0.0953.49  ± 0.391.57  ± 0.243
NR1/NR2A(T671A)2967  ±  2791.30  ± 0.0952.94  ± 0.231.29  ± 0.104