Table 1.

rREST mRNA expression in the adult rat brain

Brain structureIntensity of labeling per cell
Olfactory system
   Granular and plexiform layers of  olfactory bulb++
  Olfactory nerve layer+
Neocortex++
Hippocampal formation
  Dentate gyrus++
  CA1–CA4++
Basal ganglia
Septum and basal forebrain±
Hypothalamus and preoptic area+
Thalamus
  Reticular thalamic nucleus+
   Anteromedial and dorsal tha lamic nuclei++
  Ventral thalamic nuclei+
  Habenular nucleus++
Mesencephalon
   Substantia nigra compacta/retic ular++
  Ventral tegmental area+
  Interpendunuclar nucleus+
  Supramamillary nucleus+
  Superior colliculus±
  Red nucleus++
Cerebellum
  Granular layer+
   Cells adjacent to the Purkinje  layer++
  Deep cerebellar nuclei++
  Purkinje cell layer±
Pons
  Pontine reticular nucleus++
  Pontine nuclei++
  Trapezoid body nucleus++
  Motor trigeminal nucleus++
  Reticular nuclei++
  Spinal trigeminal nucleus+
  Facial nucleus++
Myelencephalon++
Non-neuronal cells
  Choroid plexus++
  Ependymal cells++
  Meninges (Pial)+
  • Semi-quantitative autoradiographic analysis of rREST mRNA-labeled cells in the rat brain. ++, High; +, moderate; ±, low intensity of labeling per cell; −, negative.