Table 1.

Characteristics of compound action potentials from the sciatic nerve of CGT+/+ and CGT−/− mice

+/+−/−
Amplitude at 37°C33.6  ± 5.5 mV15.9  ± 2.9 mV*
Conduction speed at 37°C32.3  ± 2.7 m/sec22.9  ± 2.2 m/sec*
Response to 4-AP (% amplitude increase)2.0  ± 1.73.1  ± 2.7
  • Compound action potentials were recorded from acutely isolated sciatic nerves from CGT+/+ (n = 3) and CGT−/− (n = 4) animals. Mean values ± SE are reported.

  • *Significant difference between values (p < 0.05, ANOVA).