Table 1.

Classification of neuronal responses during cocaine and heroin self-administration

AEAIPIPENR
n% of totaln% of totaln% of totaln% of totaln% of total
Cocaine
 mPFC111098.22018.243.68072.7
 NAc2724.365.43027.087.26154.9
Heroin
 mPFC2018.298.21412.732.76962.7
 NAc1816.265.42018.065.46861.3
  • Number and distribution of different types of neuronal responses in mPFC and NAc during separate cocaine and heroin self-administration sessions. Different categories of neuronal responses are displayed at the top of table (AE, anticipatory excitatory response; AI, anticipatory inhibitory response; PI, post-drug inhibitory response; PE, post-drug excitatory response; NR, no response). Number of neuron(n) and percentage of total are indicated in each category. A total of 110 mPFC and 111 NAc neurons were tested across cocaine and heroin sessions. A single neuron sometimes exhibited more than one type of response so it could be counted in multiple categories.