Table 1.

Uterine weights of wild-type and ApoE-KO mice

TreatmentWild-type C57B1/6JApoE-KO
Weight (mg)SEWeight (mg)SE
Control729656
OVX20*218*2
OVX + E2183*16165**15

  • OVX caused a threefold decrease, and E2 replacement caused a 2.5-fold increase in uterine weight in both WT and apoE-KO mice. There were no significant strain or strain × treatment interaction effects.

  • *p < 0.0001.

  • **p < 0.01.