Channel | K1/2/μm | n | Rectification ratio | |
---|---|---|---|---|
Symmetrical | Bi-ionic | |||
α3 | 40 (4) | 2.5 (4) | 1.05 (15) | 1.03 (12) |
α3β1b | 28 (3) | 1.9 (3) | 1.0 (12) | 1.03 (9) |
α3α4β1b | 4.0 (3) | 2.0 (3) | 1.28 (13) | 0.57 (13) |
Native | 3.4 (4) | 2.3 (4) | 1.30 (14) | 0.55 (9) |
Concentrations of cAMP, K1/2, that induced an open probability of 0.5 at +50 mV (native at −50 mV), together with Hill coefficients, n, and numbers of experiments in parentheses. Rectification ratios represent i (+50 mV)/i (−50 mV) with symmetrical Na+ or with extracellular Na+ and intracellular K+(bi-ionic condition).