Table 2.

Single-channel parameters of olfactory CNG channels

ChannelK1/2mnRectification ratio
SymmetricalBi-ionic
α340  (4)2.5  (4)1.05  (15)1.03  (12)
α3β1b28  (3)1.9  (3)1.0  (12)1.03  (9)
α3α4β1b4.0  (3)2.0  (3)1.28  (13)0.57  (13)
Native3.4  (4)2.3  (4)1.30  (14)0.55  (9)
  • Concentrations of cAMP, K1/2, that induced an open probability of 0.5 at +50 mV (native at −50 mV), together with Hill coefficients, n, and numbers of experiments in parentheses. Rectification ratios represent i (+50 mV)/i (−50 mV) with symmetrical Na+ or with extracellular Na+ and intracellular K+(bi-ionic condition).