Passage of extracellular 1-naphthyl-β-d-glucuronide across CPE cell monolayer
| NG concentration | Apical to basolateral | Basolateral to apical |
|---|---|---|
| 25 μm | ||
| NG | 0.44 ± 0.02 | 0.41 ± 0.02 |
| Sucrose | 0.47 ± 0.02 | 0.44 ± 0.02 |
| 1 mm | ||
| NG | 0.44 ± 0.01 | 0.42 ± 0.03 |
| Sucrose | 0.46 ± 0.02 | 0.45 ± 0.03 |
8 day-old LV CPE cell monolayers were exposed to either 25 μm or 1 mm NG and to tracer concentration of [14C]sucrose on the apical or basolateral membrane. All results are expressed as Pe (10−3 cm/min, mean ± SD, n = 4 filters).