Gene | Allele | PhR defect (visible at 6 dpf) | RPE defect (visible at 6 dpf) | Other cell types or tissues affected3-a |
---|---|---|---|---|
blass | blstg306a | No | Yes | Melanophores (8, renamed in this paper) |
bleached | blcth204b | No | Yes | Melanophores, ear, CNS (3, 6, 8, 14) |
blurred | blrtx3c | No | Yes | Melanophores (6, 8) |
fade out | fadtm63c | Yes | Yes | Melanophores (6, 8) |
fading vision | fdvth236a | Yes | Yes | Melanophores, CNS (3, 5, 8) |
mirage | mirtm79d | No | Yes | Melanophores (6, 8) |
ivory | Ivytm271a | Yes | Yes | Melanophores, CNS (3, 6, 8) |
quasimodo | qamtb244c | No | Yes | Melanophores, notochord (8, 9) |
sunbleached | sblto4a | Yes | Yes | Melanophores, jaw, branchial arches (6, 8, 12) |
crocodile | crotw212d | Yes | No | Other neurons (4) |
flathead | flata53c | Yes | No | CNS, jaw and branchial arches (6, 8, 12) |
tp49d | NNtp49d | Central retina | No | Kidney (1, 2) |
tz288b | NNtz288b | Central retina | No | Kidney (1, 2) |
Defects in the outer retina are visible histologically at 6 dpf. All mutants are behaviorally blind or visually impaired and have defective ERG responses (no or reduced a-wave).
↵F3-a References: 1, Brand et al. (1996); 2, Chen et al. (1996); 3, Furutani-Seiki et al. (1996); 4, Granato et al. (1996); 5, Haffter et al. (1996b); 6, Heisenberg et al. (1996); 8, Kelsh et al. (1996); 9, Odenthal et al. (1996a); 12, Schilling et al. (1996); 14,Whitfield et al. (1996).