Table 1.

Genetic complementation of mutant and wild-typeamn alleles for olfactory memory

GenotypeInitial learning1-a3 hr memory1-b
Mean ± SEMpMean ± SEMp
+/+1-c87  ± 237  ± 3
amn1/+81  ± 21-d0.29436  ± 71-d0.844
amn28A/+71  ± 41-d0.00428  ± 51-d0.138
amnX8/+80  ± 31-d0.22839  ± 41-d0.730
amn1/amn159  ± 41-d<0.00116  ± 21-d<0.001
amn28A/amn28A55  ± 31-d<0.00120  ± 41-d0.003
amnX8/amnX848  ± 41-d<0.00117  ± 41-d<0.001
amn1/amn28A67  ± 41-e 0.12621  ± 41-e0.443
amn1/amnX862  ± 41-e 0.60820  ± 41-e0.496
amn28A/amnX853  ± 41-e 0.21818  ± 51-e0.688
  • F1-a n = 6 PIs per group.

  • F1-b n = 8 PIs per group.

  • F1-c This amn+ allele, which was carried in a w (CS10) stock, is aw1118 allele that was out-crossed for 10 generations to a wild-type Can-S stock and shows normal olfactory learning/memory, olfactory acuity, and shock reactivity (Dura et al., 1993).

  • F1-d Planned pairwise comparison (α′ = 0.006) to +/+ after a one-way ANOVA, with genotype as a main effect. Data from initial learning and memory were analyzed separately.

  • F1-e Planned pairwise comparison (α′ = 0.006) toamn1/amn1after a one-way ANOVA, with genotype as a main effect. Data from initial learning and memory were analyzed separately.