Table 2.

Model parameters

SymbolDescriptionValue
αrStriosomal spectrum spacing50.0
βrStriosomal spectrum offset1.0
ΓGCalcium spike threshold0.37
αGCalcium activation rate5.0
βGCalcium passive decay rate20.0
BGCalcium concentration maximum5.0
αyCalcium recovery rate1.0
βyActivity-dependent calcium inactivation rate80.0
ΓYCalcium inactivation threshold0.18
ΓSStriosomal output threshold0.2
γsStriosomal learning gain10000
αzStriosomal learning rate0.1
wRSHypothalamus-to-ventral striatum synaptic
 weight1.2
τSVentral striatal cell response time constant30.0
τWSCS-to-ventral striatal learning rate20.0
WSmaxMaximum CS-to-ventral striatal synaptic
 weight2.5
βWSCS-to-ventral striatal weight decay rate0.2
ASVentral striatal activity passive decay rate0.7
ΓNPhasic dopamine signal threshold0.0
τPPPTN cell response time constant200.0
tUPPPTN afterhyperpolarization time constant4.0
τDDopamine cell response time constant15.0
WPDPPTN-to-dopamine cell synaptic weight50.0
WSPVentral striatal-to-PPTN cell synaptic
 weight2.0
WRPHypothalamus-to-PPTN cell synaptic weight0.8
WUPPPTN afterhyperpolarization gain140.0
ΓPPPTN output signal threshold0.135
τEmbedded ImageBaseline average dopamine time constant4.0
IDTonic input to dopamine cell0.15
hDDopamine cell maximum hyperpolarization0.1
VIIntegrate-and-fire (IAF) model output0.5
RIAF model membrane resistance1333
CIAF model membrane capacitance0.025
ςnoiseIAF Gaussian noise input0.4
RDAIAF dopamine cell membrane resistance80
RPPTNIAF PPTN cell membrane resistance6667
CPPTNIAF PPTN cell membrane capacitance0.005
ςPPTNIAF PPTN cell Gaussian noise input0.1