Experimental condition | Percentage of slices with DC negative shift (n) | Onset of DC negative shift (n) | Evoked EPSP (percentage of initial EPSP amplitude) |
---|---|---|---|
Control | 0 (0/9)1-a | 110 ± 111-c | |
OGD (2 min) | 33 (2/6) | 1.0 (2)1-b | |
OGD (5 min) | 67 (4/6) | 1.5 ± 0.5 (4) | |
OGD (12 min) | 100 (5/5) | 4.75 ± 1.3 (5) | |
OGD (42 min) | 100 (8/8) | 5.00 ± 1.9 (8) | |
OGD/ROX-36°C | 100 (6/6) | 5.9 ± 0.75 (6) | 16 ± 8.5 |
OGD/ROX-31°C | 43 (7/7) | 8.5 ± 0.76 (3) | 65 ± 16 |
↵F1-a Ratio in parentheses is number of slices exhibiting DC negative shift per total number of slices in experimental group.
↵F1-b Onset (mean minutes of oxygen/glucose deprivation ± SEM) of DC negative shift for those slices (n) exhibiting a shift during the OGD period. See Materials and Methods for electrophysiological protocol.
↵F1-c Differences among treatment and control groups were statistically significant (p < 0.05; Kruskal–Wallis on rank ANOVA with Bonferroni correction).