Table 1.

Peak fear

ContextTone
Experiment 1
 Remote
  Sham95.8  ± 2.075.8  ± 8.2p = 0.02*
  DH96.6  ± 2.475.0  ± 11.7p = 0.2
p > 0.6p > 0.9
 Recent
  Sham95.8  ± 1.680.0  ± 6.3p = 0.01*
  DH71.6  ± 8.471.6  ± 12.5p > 0.99
p = 0.02*p > 0.9
Experiment 2
  Sham99.3  ± 0.784.0  ± 7.6p = 0.03*
  DH79.7  ± 9.192.2  ± 4.7p = 0.2
p < 0.01*p > 0.8
  • Peak freezing (mean ± SEM) was computed by taking each rat’s maximum freezing for any continuous minute during each of the 8-min context and 6-min (post-baseline) tone fear tests. Paired comparisons contrast context and tone freezing within-subjects using the Wilcoxon signed-rank post hoc; unpaired comparisons contrast Sham and DH groups for each test using the Mann–Whitney U post hoc. For both Experiments 1 and 2, DH lesions produced significant impairments in average (Figs. 3-5) and peak (above) recent context fear but not remote context or tone fear. For Sham animals, peak (above) and average (Figs. 3-5) context fear was greater than, or equivalent to, but not weaker than tone fear.