Table 1.

Distribution of nicotinic receptor actions among the different layers in the CA1 region of the hippocampus

Fast response (%)Fast and slow response (%)No response (%)Total
Stratum oriens26 (32)52 (63)4 (5)82
Stratum pyramidale16 (44)2 (6)18 (50)36
Pyramidal cell2 (13)*0 (0)13 (87)15
Stratum radiatum21 (100)0 (0)0 (0)21
Stratum lacunosum-moleculare16 (80)4 (20)**0 (0)20
  • * and ** indicate very small responses <15 pA when measured in voltage clamp at VH = −70 mV. As discussed in Results, neurons with both fast and slow responses are somewhat over-represented because these cells could be visually identified and selected later in the study.