Number of transgenic (NTG) and wild-type (NWT) mice analyzed in the 5 month treatment groups
| Treatment | NTG | SeedingTG | NWT | SeedingWT |
|---|---|---|---|---|
| AD case 1 | 5a,b | Yes | 3 | No |
| AD case 2 | 5 | Yes | — | — |
| AD case 3 | 42-a | Yes | — | — |
| AD case 4 | 5 | Yes | — | — |
| Aged control | 22-a | Slight | 3 | No |
| Young control | 4 | No | — | — |
| Sham (HBSS) | 3 | No | 3 | No |
| Untreated | 3 | No | 3 | No |
| Total mice | 31 | 12 |
↵F2-a One mouse in each of these groups died during the 5 month incubation period; the numbers shown indicate the mice that remained for analysis.
F2-b These five mice represent two separate experiments. Three mice were injected in the initial study (one died during incubation); 6 months later, an additional three mice were injected with extract from the same case. All five mice showed similar levels of extract-induced Aβ-immunoreactivity.