β-Galactosidase expression | ||
---|---|---|
SAL | FLU | |
Amygdala | 173 ± 15 | 217 ± 11* |
Cortex | 196 ± 17 | 241 ± 9* |
CA3 | 138 ± 4 | 184 ± 17* |
Dentate gyrus | 135 ± 7 | 141 ± 12 |
Hypothalamus | 125 ± 8 | 167 ± 8* |
Thalamus | 120 ± 4 | 152 ± 14* |
Mice received a chronic (14 d) administration of vehicle (SAL) or fluoxetine (FLU) and were killed 6 h after the last injection. Levels of β-galactosidase were determined by immunohistochemistry as described in Materials and Methods. Levels of β-galactosidase labeling were quantified by densitometry of digitalized images as described in Materials and Methods. The data are the mean ± SEM;n = 6 separate determinations. *p < 0.05 compared with saline (Kruskal–Wallis).