Table 2.

Phenotype and percentage chimerism^ain Unc5h3/Unc5h3↔ROSA26 chimeras

Chimera No.	Estimate of phenotype^2-b		Within normal cerebellum (%)				In ectopias (%)
Chimera No.	Intracerebellar	Extracerebellar	GC-Ant^2-c	GC-Post^2-c	PC-Ant.	PC-Post.	PC	GC
1	1.5^2-d	2.0	10	10	10	10	10	70 (close)
								95 (far)^2-e
2	2.5	2.5	10	20	35	30	50–60	90+
3	3.0	3.5	20	40	56	55	51	90+
4	2.5	3.0	30	40	37	45	33	90
5	4.0	4.5	45	65	33	42	34	90

GC-Ant., Granule cell-anterior; GC-Post., granule cell-posterior; PC-Ant., Purkinje cell-anterior; PC-Post., Purkinje cell-posterior.
F2-a The percentage of cells that areUnc5h3/Unc5h3.
↵F2-b Range: 1–5 with 1 = nonmutant phenotype while 5 = Unc5h3 mutant phenotype.
↵F2-c The percentage chimerism for the nonectopic granule cells is an estimate because of variations in distribution of granule cells across the cerebellum.
↵F2-d There were no obvious intracerebellar ectopias in this chimera but only hints that the border with the white matter may be disrupted in a few locations.
↵F2-e Close refers to cells that are near the edge of the normal cerebellum, and far refers to the granule cells that are more distal to the normal cerebellum.